PHARMACEUTICAL DOSAGE FORM FOR ORAL ADMINISTRATION OF A BCL-2 FAMILY INHIBITOR

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United States of America Patent

APP PUB NO 20170189426A1
SERIAL NO

15466673

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Abstract

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The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl) propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders

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Patent Owner(s)

Patent OwnerAddress
ABBVIE DEUTSCHLAND GMBH & CO KGMAX-PLANCK-RING 2A WIESBADEN 65205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Knobloch, Martin Neuhofen, DE 11 109
Kostelac, Drazen Roemerberg, DE 11 66
Liepold, Bernd Dossenheim, DE 40 414
Packhaeuser, Claudia Munich, DE 5 51
Steiger, Norbert Lingenfield, DE 10 69

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