POLYMERS FOR THERMALLY-REGULATED RELEASE OF HNO AND OTHER MOLECULES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20170202874A1
SERIAL NO

15405988

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Multivalent scaffolds configured to facilitate drug release upon exposure to a stimulus, such as heat, or light, are described herein. The multivalent scaffolds are covalently bound to a moiety that is susceptible to decomposition upon exposure to stimulus. The moiety releases HNO upon decomposition. In some embodiments, the moiety is in turn linked to an agent to be delivered, such as a therapeutic agent, which is released from the multivalent scaffolds when the moiety decomposes. In some embodiments, the moiety is a 1,2-oxazine moiety. In some embodiments, the multivalent scaffold is a polymer. A plurality of 1,2-oxazine moieties can be covalently bound as side chains to the backbone of the polymer.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNVERSITY OF WASHINGTON4545 ROOSEVELT WAY NE SUITE 400 SEATTLE WA 98105

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boydston, Andrew J Seattle, US 19 118
Church, Derek C Seattle, US 3 3
Yakelis, Neal A Federal Way, US 2 2

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation