Systems and methods for encoding genetic variation for a population
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United States of America Patent
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Oct 29, 2019
Grant Date -
Jul 27, 2017
app pub date -
Jan 26, 2016
filing date -
Jan 26, 2016
priority date (Note) -
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Abstract
In one embodiment, a method of encoding variation data for a population comprises receiving, by a variant encoding engine executing on a processor, information describing genetic variation of a population of individuals. The information comprises a plurality of variable sites within the reference genome of the population and the genotypes of a plurality of individuals in the population with respect to those variable sites. The method further comprises selecting an encoding strategy for the information based on the characteristics of the genetic variation across the population, and encoding the information according to the selected encoding strategy. In certain embodiments, selecting an encoding strategy may comprise determining the variability of a variable site within the population, and encoding information associated with the variable site based on the variability.
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