CELL CULTURE DEVICE, METHOD OF FORMING THE SAME, AND METHOD OF PARTIALLY DETACHING STEM CELLS FROM THE SAME
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United States of America Patent
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Aug 3, 2017
app pub date -
Jan 29, 2016
filing date -
Jan 29, 2016
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Abstract
A cell culture device includes a container having a surface and a plurality of nano-bristles immobilized to the surface. The nano-bristles are made of styrene copolymer or oligopeptide. A method of partially detaching stem cells from a cell culture device includes: seeding stem cells onto the plurality of nano-bristles, culturing the stem cells, detaching a portion of the stem cells from the nano-bristles by a change in temperature or a shear force, and harvesting the portion of the stem cells.
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