Nanocomposites and nanoagents for detection and treatment of a target of interest and methods of making and using same
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United States of America Patent
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May 25, 2021
Grant Date -
Aug 3, 2017
app pub date -
Apr 14, 2017
filing date -
Feb 17, 2014
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Abstract
A nanocomposite for detection and treatment of a target of interest including tumor cells or pathogens includes at least one nanostructure, each nanostructure having a core and a shell surrounding the core; a reporter assembled on the shell of each nanostructure; and a layer of a treating agent and a targeting agent conjugated to the reporter. In use, the nanocomposite targets to the target of interest according to the targeting agent and releases the treating agent and the nanostructure therein for therapeutic treatment of the target of interest, and the target of interest transmits at least one signature responsive to the reporter for detection of the target of interest.
First Claim
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
- BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS N. A.
International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- B82Y:SPECIFIC USES OR APPLICATIONS OF NANO-STRUCTURES; ....
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- B01J:CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, CO....
- H01F:MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF M....
- A61N:ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY;....
- B32B:LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA....
- [Classification Symbol]
- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Biris, Alexandru S | Little Rock, US | 58 | 406 |
Nima, Zeid A | Little Rock, US | 6 | 1 |
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