Nanocomposites and nanoagents for detection and treatment of a target of interest and methods of making and using same

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United States of America Patent

PATENT NO 11016089
APP PUB NO 20170219575A1
SERIAL NO

15487683

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A nanocomposite for detection and treatment of a target of interest including tumor cells or pathogens includes at least one nanostructure, each nanostructure having a core and a shell surrounding the core; a reporter assembled on the shell of each nanostructure; and a layer of a treating agent and a targeting agent conjugated to the reporter. In use, the nanocomposite targets to the target of interest according to the targeting agent and releases the treating agent and the nanostructure therein for therapeutic treatment of the target of interest, and the target of interest transmits at least one signature responsive to the reporter for detection of the target of interest.

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Patent Owner(s)

  • BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS N. A.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biris, Alexandru S Little Rock, US 58 406
Nima, Zeid A Little Rock, US 6 1

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