Selective inhibitors of constitutive androstane receptor

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United States of America Patent

PATENT NO 9908890
SERIAL NO

15519109

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Abstract

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The compounds of the invention are antagonists of CAR, with specificity for CAR over other proteins including PXR. The disclosed compounds are useful in treating or controlling cell proliferative disorders, in particular oncological disorders, such as cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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Patent Owner(s)

Patent OwnerAddress
ST JUDE CHILDREN'S RESEARCH HOSPITAL262 DANNY THOMAS PLACE MEMPHIS TN 38105

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Taosheng Germantown, US 15 12
Cherian, Milu Memphis, US 1 0
Lin, Wenwei Memphis, US 11 3

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