Markers for mood disorders

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United States of America Patent

PATENT NO 10745736
APP PUB NO 20170226559A1
SERIAL NO

15514956

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Abstract

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Disclosed is a method for diagnosing a mood disorder or susceptibility to a mood disorder, including depressive disorders and bipolar disorder, from a biological sample taken from a subject. The method includes detecting markers of monoamine oxidase-A (MAO-A) in the biological sample; determining MAO-A concentration from the markers; and correlating the MAO-A concentration in the biological sample to a control group which does not have a mood disorder in order to diagnose or determine susceptibility to the mood disorder in the subject. Also disclosed is a method of detecting peripheral markers of MAO-A for the diagnosis of a mood disorder or susceptibility to a mood disorder. Also provided are polypeptide markers.

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Patent Owner(s)

Patent OwnerAddress
CENTRE FOR ADDICTION AND MENTAL HEALTH100 STOKES STREET BELL GATEWAY BUILDING 6TH FLOOR TORONTO M6J 1H4

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ackloo, Suzanne Toronto, CA 2 32
Chen, Jian Toronto, CA 1588 23569
Dharsee, Moyez Toronto, CA 1 0
Evans, Ken Toronto, CA 11 52
Meyer, Jeffrey Toronto, CA 16 194

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