Optical biosensor referencing method

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United States of America Patent

PATENT NO 10473589
APP PUB NO 20170227458A1
SERIAL NO

15494120

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Abstract

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A referencing method for an optical biosensor system using a single sensing region is provided. The method involves limiting the ligand immobilized in a single sensing region to only a portion thereof. In one embodiment, this is accomplished by selectively deactivating a portion of the sensing surface to prevent immobilization of ligand to that portion. As a result, a reference response can be recorded in the same sensing region as a molecular interaction response. Thus, the bulk refractive index can be accurately accounted for in measuring the kinetics of a molecular interaction.

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Patent Owner(s)

  • MOLECULAR DEVICES, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Quinn, John Gerard Edmond, US 12 50

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