INJECTABLE FORMULATIONS OF ASENAPINE
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United States of America Patent
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Jun 11, 2015
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Aug 14, 2014
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Abstract
The invention provides nano- and/or microparticles comprising asenapine or a pharmaceutically acceptable salt thereof, wherein said asenapine or said pharmaceutically acceptable salt thereof is embedded in a polymer matrix or encapsulated by a polymer shell, wherein the polymer matrix or the polymer shell comprises a polymer selected from polylactide, polyglycolide, and polyester copolymers comprising copolymerized units of lactic acid and/or glycolic acid, as well as a process for their production. Moreover, the invention provides pharmaceutical compositions comprising these particles.
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