LILRB2 and notch-mediated expansion of hematopoietic precursor cells

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10370643
APP PUB NO 20170260508A1
SERIAL NO

15313043

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The current disclosure describes methods of expanding precursor cells for hematopoietic transplantation in subjects. The methods culture precursor cells in media containing an immobilized high molecular weight LILRB2 agonist or an LILRB2 agonist in combination with a Notch agonist. The expanded cells can be used to treat a variety of hematopoietic disorders.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • FRED HUTCHINSON CANCER RESEARCH CENTER; BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernstein, Irwin D Seattle, US 21 102
Deng, Mi Plano, US 10 14
Lu, Zhigang Irving, US 16 75
Zhang, Chengcheng Southlake, US 31 136
Zheng, Junke Shanghai, CN 7 26

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Feb 6, 2027
11.5 Year Payment $7400.00 $3700.00 $1850.00 Feb 6, 2031
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00