TRUNCATED LYSOSOMAL ACID LIPASE
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United States of America Patent
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Dec 21, 2016
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Mar 2, 2012
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Abstract
Recombinant human lysosomal acid lipase (rhLAL) containing an N-terminal truncation, a composition of truncated recombinant human LAL (TLAL), an isolated mixture comprising TLAL and at least one other form of rhLAL are disclosed. A method of purifying TLAL from a mixture of LAL proteins, pharmaceutical compositions comprising TLAL and methods of producing TLAL are further disclosed.
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