DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

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United States of America Patent

APP PUB NO 20170267731A1
SERIAL NO

15505357

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Abstract

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Disintegrin variants that bind specifically to one or more of α5β1 and αv integrins, such as αvβ1, αvβ3, αv7β5, αvβ6 and αvβ8, but with reduced binding activity to αIIbβ3, are described. Also described are uses of the disintegrin variants for the treatment or prevention of a disease associated with an αv integrin or an α5β1 integrin.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL CHENG KUNG UNIVERSITYNO 1 DAXUE RD EAST DIST TAINAN CITY

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Inventor Name Address # of filed Patents Total Citations
CHUANG, Woei-Jer Tainan City, TW 9 36

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