Methods of detecting target nucleic acids

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United States of America Patent

PATENT NO 10196680
APP PUB NO 20170275678A1
SERIAL NO

15614606

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Abstract

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The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.

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Patent Owner(s)

  • APPLIED BIOSYSTEMS, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mullah, Khairuzzaman Bashar Union City, US 37 1068
Sharaf, Muhammad A Oakland, US 24 321
Woudenberg, Timothy San Francisco, US 30 442

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