ALK AND ROS KINASE IN CANCER

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United States of America Patent

SERIAL NO

15616111

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Abstract

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The invention provides a method for identifying a patient with cancer or suspected of having cancer as a patient likely to respond to an ALK- and/or ROS-inhibiting therapeutic, comprising: contacting a biological sample from a patient with a first reagent that specifically binds a polypeptide having ROS kinase activity and a second reagent that specifically binds to a polypeptide having ALK knase activity, and detecting whether the first reagent or the second reagent specifically binds to the biological sample, wherein detection of binding of either the first reagent or the second reagent to the biological sample identifies the patient as a patient likely to respond to an ALK-inhibiting and/or ROS-inhibiting therapeutic.

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Patent Owner(s)

Patent OwnerAddress
CELL SIGNALING TECHNOLOGY INCDANVERS MA 01923

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Crosby, Katherine Eleanor Middleton, US 17 13
Haack, Herbert South Hamilton, US 31 73
Rimkunas, Victoria McGuinness Reading, US 12 13

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