METHOD OF TREATING PATIENTS NON-RESPONSIVE TO PALONOSETRON
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United States of America Patent
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Oct 5, 2017
app pub date -
Jun 19, 2017
filing date -
Feb 5, 2013
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Abstract
A method for treating chemotherapy-induced nausea and vomiting in individuals undergoing chemotherapy and previously treated with, and whom failed to respond to, a 5-HT3 antagonist other than granisetron is described. Individuals who fail to respond to, for example, palonosetron, as evidenced by an inadequate prevention or attenuation of acute or delayed chemotherapy-induced nausea and vomiting, are treated with a semi-solid drug delivery vehicle that provides a sustained release of granisetron.
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