Methods for inhibiting angiogenesis in a subject in need thereof

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United States of America Patent

PATENT NO 10870708
APP PUB NO 20170283508A1
SERIAL NO

15476154

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Abstract

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In one aspect, the present invention provides methods for preventing, treating, reverting and/or delaying angiogenesis in a mammalian subject suffering from, or at risk for developing, an angiogenesis-dependent disease or condition, comprising administering to the subject an amount of a MASP-2 inhibitory agent effective to inhibit angiogenesis. In some embodiments of these aspects of the invention, the MASP-2 inhibitory agent is a MASP-2 antibody or fragment thereof.

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Patent Owner(s)

  • UNIVERSITY OF LEICESTER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Demopulos, Gregory A Mercer Island, US 169 2686
Dudler, Thomas Bellevue, US 55 395
Schwaeble, Hans-Wilhelm Mountsorrel, GB 76 652
Tjoelker, Larry Kirkland, US 4 53

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