Modified Cells Evoking Reduced Immunogenic Responses
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Jun 7, 2017
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Jan 17, 2015
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Abstract
The present disclosure describes composition, methods, and systems associated with a genetically modified stem cell. The modified stem cell includes a reduced amount of Major Histocompatibility Complex II (MHC II) as compared to a corresponding wild-type cell. Further, the modified cell has decreased immunogenicity as compared to the corresponding wild-type cell.
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