Screening of large-scale genetic interaction networks

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United States of America Patent

PATENT NO 11017880
APP PUB NO 20170286595A1
SERIAL NO

15475347

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Disclosed in some examples are methods including selecting a first plurality of single gene mutants from a pool of possible single gene mutants of an organism. The first plurality of single gene mutants is less than a number of possible single mutants. A computer processor is used to iteratively select a second plurality of single gene mutants by selecting single gene mutants from the pool of possible single gene mutants that increases a sum of products of similarities between the first plurality of single gene mutants and corresponding functional relationships. The second plurality of single gene mutants is larger in number than the first plurality of single gene mutants, and wherein the second plurality of single gene mutants is less than the number of possible single gene mutants of the organism. A set of genes is outputted comprising the first and second pluralities of single gene mutants.

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Patent Owner(s)

  • REGENTS OF THE UNIVERSITY OF MINNESOTA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deshpande, Raamesh Fremont, US 1 0
Myers, Chad L Arden Hills, US 3 3
Nelson, Justin St Paul, US 23 301
Simpkins, Scott William Saint Paul, US 1 0

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