PCSK9 Inhibitors and Methods of Use Thereof

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United States of America Patent

SERIAL NO

15509627

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Abstract

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The present invention relates to compositions and methods for treating lipid disorders in a subject. In one embodiment, the compositions of the present invention can be used to inhibit protease proprotein convertase subtilisin-like kexin type 9 (PCSK9). In another embodiment, the compositions of the present invention can be used to disrupt the protein-protein interaction between PCSK9 and low-density lipoprotein receptor (LDLR).

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Patent Owner(s)

Patent OwnerAddress
TEMPLE UNIVERSITY--OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONBROAD AND MONTGOMERY AVENUE PHILADELPHIA PA 19122

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abou-Gharbia, Magid Exton, US 19 88
Childers, Wayne E New Hope, US 42 72

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