Wideband isolation directed by ion mobility separation for analyzing compounds

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United States of America Patent

PATENT NO 10267765
APP PUB NO 20170299550A1
SERIAL NO

15099178

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In an ion mobility-mass spectrometry (IM-MS) system, an ion mass-isolated data set is acquired by operating a mass filter to apply a mass isolation window having an m/z width such that the mass isolation window moves through a sequence of window positions, each window position being defined by an IM drift time value and an m/z ratio value. The m/z width of the mass isolation window and the sequence of window positions are determined such that the mass isolation window captures ions in a region of interest of a larger all-ions data set. The isolation window may be a wideband isolation window. In comparison to the all-ions data set, the mass-isolated data set may yield reduced ion signal interference and increased selectivity for analytes of interest.

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Patent Owner(s)

  • AGILENT TECHNOLOGIES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kurulugama, Ruwan T Livermore, US 10 121
Overney, Gregor T San Jose, US 16 159
Stafford, George San Jose, US 20 569
Wang, Jun San Jose, US 1949 16792

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