Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications

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United States of America Patent

PATENT NO 10183055
APP PUB NO 20170304391A1
SERIAL NO

15401944

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/or impairment, pain, and traumatic brain injury.

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Patent Owner(s)

  • ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Forte, Brittany Tucson, US 5 1
Hay, Meredith Tucson, US 15 8
Jones, Evan Tucson, US 60 725
Konhilas, John Tucson, US 21 39
Milnes, Tally Tucson, US 6 1
Polt, Robin L Tucson, US 24 50
Szabo, Lajos Tucson, US 46 113
Vanderah, Todd Tucson, US 6 1

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