CARM1 INHIBITORS AND USES THEREOF

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United States of America Patent

SERIAL NO

15511503

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Abstract

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Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein R1, R2a, R2b, R3 and Ring B are as defined herein, and Ring A is a group of Formula (A-i), (A-ii), or (A-iii): wherein R, R, R, R, and R are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.

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Patent Owner(s)

Patent OwnerAddress
EPIZYME INCCAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Babine, Robert E Carlsbad, US 19 497
Chesworth, Richard Concord, US 171 3995
JIn, Lei Wellesley, US 207 2561
Moradei, Oscar Miguel Burlington, US 32 929
Shapiro, Gideon Gainesville, US 125 2170

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