HERIPENES WITH PAIN-RELIEVING EFFECT, ACTIVE SUBSTANCES OF Hericium erinaceus MYCELIUM AND THE PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE HERIPENES OR ACTIVE SUBSTANCES

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United States of America Patent

SERIAL NO

15508369

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Abstract

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The present invention is related to an active substance of Hericium erinaceus having a pain-relieving effect, and a pharmaceutical composition including the active substance. The active substance is prepared using the following steps: (a) inoculating a mycelium of H. erinaceus on an agar plate and incubating at 15-32° C. for 8-16 days; (b) inoculating the incubated H. erinaceus mycelia from step (a) into a medium in a flask and incubating at 20-30° C. and pH 4.5-6.5 for 3-5 days; (c) inoculating the incubated H. erinaceus mycelia from step (b) into a medium in a fermentation tank and incubating at 24-32° C. and pH 4.5-5.5 for 8-16 days to obtain a fermented medium of the H. erinaceus mycelia; and (d) desiccating the fermented medium of the H. erinaceus mycelia from step (c) to obtain the powder of the H. erinaceus mycelia, which is further purified and isolated to obtain a novel compound of H. erinaceus.

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Patent Owner(s)

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GRAPE KING BIO LTDNO 402 SEC 2 JINLING RD PINGZHEN DISTRICT TAOYUAN CITY 32471

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Chien-Chih Taipei City, TW 199 1412
Chen, Chin-Chu Taoyuan City, TW 67 1333
Chen, Wan-Ping Taoyuan City, TW 5 1
Chu, Wei-Ching Taoyuan City, TW 2 1
Hsu, Jui-Hsia Taoyuan City, TW 6 2
Lee, Li-Ya Taoyuan City, TW 7 2
Lin, Ting-Wei Taoyuan City, TW 24 105
Liu, Pei-Shan Taipei City, TW 6 1

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