Methods and compositions related to retinoid receptor-selective pathway

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United States of America Patent

PATENT NO 10087156
APP PUB NO 20170313668A1
SERIAL NO

15435125

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Abstract

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Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenviroment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients.

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Patent Owner(s)

  • SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE; XIAMEN UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Pei-Qiang Xiamen, CN 2 1
Liu, Wen La Jolla, US 137 1386
Su, Ying San Diego, US 38 297
Zhang, Xiao-kun San Diego, US 20 277
Zhou, Hu San Diego, US 21 27

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