Fragments of syndecan-2 having anti-angiogenic activity

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United States of America Patent

PATENT NO 10766942
APP PUB NO 20170320929A1
SERIAL NO

15520149

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Abstract

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The present invention provides an anti-angiogenic peptide comprising an amino acid sequence having at least 70% identity to amino acid residues 123-140 of SEQ ID NO 1 or amino acid residues 24-141 of SEQ ID NO 2. The invention also provides nucleic acid constructs encoding such peptides, and vectors and cells comprising such nucleic acid constructs. The invention further provides pharmaceutical compositions comprising the peptides or nucleic acid constructs of the invention, and the use of peptides, nucleic acid constructs or pharmaceutical compositions of the invention to treat diseases associated with angiogenesis.10

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Patent Owner(s)

Patent OwnerAddress
QUEEN MARY UNIVERSITY OF LONDONLONDON GREATER LONDON E1 4NS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Rossi Giulia London, GB 2 0
Whiteford, James London, GB 3 43

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