CANCER MARKER AND CANCER DETERMINATION METHOD
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United States of America Patent
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Aug 18, 2015
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Aug 18, 2014
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Abstract
The invention relates to a cancer marker, consisting of a portion of or all of the nucleotide sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from a cell, and being continuous nucleotide sequences comprising at least the nucleotide sequence represented by SEQ ID NO: 2 or 3, wherein 30% or more of cytosines of the -CG- sequences present in said nucleotide sequence are methylated, and method for determining canceration of a cell on the basis of methylation ratio, wherein said methylation ratio is measured by a bisulfate reaction for a portion of or all of cytosines of the -CG- sequences present in the nucleotide sequence represented by SEQ ID NO: 1 in a FOXB2 gene derived from a cell.
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