METHOD AND REAGENT FOR DETECTING OVARIAN CLEAR CELL ADENOCARCINOMA

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United States of America Patent

SERIAL NO

15529550

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Abstract

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The present invention aims to provide a method for detecting, with high sensitivity and specificity, ovarian clear cell adenocarcinoma, which is highly malignant, among benign and malignant ovarian tumors having various tissue types, and a reagent that can be used for the method. The present invention provides NT-TFPI2, which is a novel processed tissue factor pathway inhibitor 2 polypeptide, as a new detection marker for ovarian clear cell adenocarcinoma. The detection of ovarian clear cell adenocarcinoma is carried out by measuring the amount of NT-TFPI2, or the total amount of NT-TFPI2 and intact TFPI2. The reagent for detecting ovarian clear cell adenocarcinoma contains an antibody that specifically recognizes NT-TFPI2 and intact TFPI2.

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Patent Owner(s)

Patent OwnerAddress
TOSOH CORPORATION4560 KAISEI-CHO SHUNAN-SHI YAMAGUCHI 746-8501
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITYYOKOHAMA-SHI KANAGAWA 236-0027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ARAKAWA, Noriaki Yokohama-shi, JP 12 205
HIRANO, Hisashi Yokohama-shi, JP 8 38
MIYAGI, Etsuko Yokohama-shi, JP 6 6
OHTAKE, Norihisa Ayase-shi, JP 11 1

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