Transgenic mouse for the assessment of thyroid hormone (TH) action

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United States of America Patent

PATENT NO 10694724
APP PUB NO 20170325429A1
SERIAL NO

15531100

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Abstract

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A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.

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Patent Owner(s)

  • KISÉRLETI ORVOSTUDOÁNYI KUTATÓINTÉZET

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erdélyi, Ferenc Budapest, HU 1 0
Fekete, Csaba Budapest, HU 2 0
Gereben, Balázs Budapest, HU 1 0
Mohácsik, Petra Budapest, HU 1 0
Szabó, Gábor Budapest, HU 8 18

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