Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10736974
APP PUB NO 20170333576A1
SERIAL NO

15521149

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Carbamate and beta-amino acid urea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used for imaging cells and tumors that express PSMA or for cancer radiotherapy. These compounds also can comprise a fluorescent dye and be used for imaging cells and tumors that express PSMA or for photodynamic therapy.

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Patent Owner(s)

Patent OwnerAddress
THE JOHNS HOPKINS UNIVERSITY3400 NORTH CHARLES STREET BALTIMORE MD 21205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Ying Lutherville-Timonium, US 891 19090
Mease, Ronnie C Fairfax, US 48 453
Pomper, Martin G Baltimore, US 86 426
Ray, Sangeeta Ellicott City, US 42 258
Yang, Xing Baltimore, US 152 1036

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