Tetrafunctional bacteriophage

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10799542
APP PUB NO 20170340684A1
SERIAL NO

14889805

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Abstract

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The invention provides a recombinant targeted bacteriophage for expressing a transgene in a target cell transduced with the bacteriophage. The bacteriophage comprises a first nucleic acid sequence encoding a pill capsid minor coat protein that is configured to display a cell-targeting ligand for enabling delivery of the bacteriophage to a target cell, a second nucleic acid sequence encoding at least one pVIII capsid major coat protein that is configured to display a foreign peptide thereon, and a transgene which encodes a protein which exerts a biological effect on the target cell.

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Patent Owner(s)

  • IMPERIAL COLLEGE INNOVATIONS LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hajitou, Amin London, GB 12 21
Yata, Teerapong London, GB 5 11

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