Molecular indexing of internal sequences

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United States of America Patent

PATENT NO 10640763
SERIAL NO

15596364

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Abstract

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The present disclosure relates to compositions, methods and kits for labeling an internal sequence of a target nucleic acid molecule with molecular barcodes. In some embodiments, the methods comprise intramolecular circulation of a labeled target nucleic acid molecule. Further provided methods for generating sequencing libraries comprising overlapping fragments covering the full length of a target nucleic acid molecule, sequencing the libraries using the methods disclosed herein, and methods of analyzing sequencing results therefrom.

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Patent Owner(s)

Patent OwnerAddress
BECTON DICKINSON AND COMPANY1 BECTON DRIVE MC110 FRANKLIN LAKES NJ 07417-1880

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fu, Glenn Menlo Park, US 45 3937
Shum, Eleen Menlo Park, US 44 1120

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