VLP WITH A FUSION PROTEIN

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United States of America Patent

SERIAL NO

15533378

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Abstract

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The disclosure relates to a fusion protein comprising a VP1 binding protein and an exogenous peptide, wherein the exogenous peptide comprises a cargo-securing peptide (CSP) and/or an endosome translocating peptide (ETP) and to virus like particles (VLP) comprising the fusion protein for use as drug delivery system. Also provided are polynucleotides encoding the fusion protein, suitable expression vectors, host cells, production methods for the fusion protein and the VLP comprising the fusion protein.

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Patent Owner(s)

Patent OwnerAddress
LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO KGLUDWING-ERHARD-ALLEE 2 BONN 53175

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
FRANKEN, SEBASTIAN BONN, DE 3 0
GLASSMANN, ALEXANDER BONN, DE 6 1
TEMME, NADINE BONN, DE 3 0

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