SOLID DISPERSION FORMULATIONS OF ANTIVIRAL COMPOUNDS

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United States of America Patent

SERIAL NO

15537564

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure is directed to solid dispersion formulations comprising an NS5A inhibitor compound, elbasvir (dimethyl N,N′-([(6S)-6-phenylindolo [1,2- c][1,3]benzoxazine-3,10-diyl]bis {1H-imidazole-5,2-diyl-(2S)-pyrrolidine-2,1-diyl[(2S)-3-methyl-l-oxobutane-1,2-diyl]})di-carbamate), or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and optionally a pharmaceutically acceptable surfactant. The present disclosure is also directed to solid dispersion formulations, blended compositions and pharmaceutical dosage forms containing or made from these solid dispersion formulations, and the methods for making these solid dispersion formulations, blended compositions and pharmaceutical dosage forms.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME CORP126 E LINCOLN AVENUE RY86-2011A RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MILLER, Elise Gilbertsville, US 2 0
MOSER, Justin David Collegeville, US 3 0
SHETH, Agam Plymouth Meeting, US 2 0
SOCIA, Adam J Blue Bell, US 2 0
SUNDARARAJAN, Pavithra North Wales, US 2 0
WAGNER, Angela M Austin, US 3 0

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