HYPDH INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES

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United States of America Patent

SERIAL NO

15545818

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Abstract

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Provided herein are compounds of Formula (I), Formula (II), and Formula (III), and compositions comprising the same, as well as methods of use thereof for controlling or inhibiting the formation of calcium oxalate kidney stones, inhibiting the production of glyoxylate and/or oxalate, and/or inhibiting hydroxyproline dehydrogenase (HYPDH).

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Patent Owner(s)

Patent OwnerAddress
WAKE FOREST UNIVERSITY HEALTH SCIENCESMEDICAL CENTER BLVD WINSTON-SALEM NC 27157

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holmes, Ross P Birmingham, US 4 0
Lowther, W Todd Pfafftown, US 6 1
Yohannes, Daniel Winston-Salem, US 49 275

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