SYNTHESIS OF A BRUTON?S TYROSINE KINASE INHIBITOR

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United States of America Patent

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15542848

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Described herein is the synthesis of Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo [3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one.

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JANSSEN PHARMACEUTICA NV2340 BEERSE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benhaim, Cyril Beerse, BE 1 2
Chen, Wei Fremont, US 2011 24064
Goldman, Erick Concord, US 40 499
Horvath, Andras Beerse, BE 37 73
Pye, Philip Beerse, BE 15 70
Smyth, Mark S Foster City, US 75 1296
Verner, Erik J Belmont, US 53 2388

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