SYNTHESIS OF A BRUTON?S TYROSINE KINASE INHIBITOR

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United States of America Patent

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15542848

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Described herein is the synthesis of Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo [3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one.

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JANSSEN PHARMACEUTICA NVTURNHOUTSEWEG 30 BEERSE B-2340

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benhaim, Cyril Beerse, BE 1 0
Chen, Wei Fremont, US 1758 22268
Goldman, Erick Concord, US 38 488
Horvath, Andras Beerse, BE 36 64
Pye, Philip Beerse, BE 14 65
Smyth, Mark S Foster City, US 74 1288
Verner, Erik J Belmont, US 50 2335

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