Solid supports and phosphoramidite building blocks for oligonucleotide conjugates

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United States of America Patent

PATENT NO 10781175
APP PUB NO 20180016232A1
SERIAL NO

15650773

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Abstract

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Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.

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Patent Owner(s)

  • AM CHEMICALS LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gogoi, Khirud San Marcos, US 6 34
Guzaev, Andrei Pavel Escondido, US 5 10
Vvedenskiy, Vladimir Y San Diego, US 5 9

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