Methods for evaluation of the effectiveness of a drug or drug candidate in treating an inflammatory bowel disease by use of multiplexed assay kit comprising various biomarkers
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United States of America Patent
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Jul 14, 2020
Grant Date -
Jan 18, 2018
app pub date -
Sep 27, 2017
filing date -
Dec 9, 2004
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Abstract
Disclosed are methods for conducting diagnostic tests for the detection of the inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Also described are methods for monitoring a patient by administering tests of the present invention. Also described are methods for monitoring patient's treatment by administering tests of the present invention. Also described are methods for evaluating the effectiveness of a drug or a drug candidate by administering tests of the present invention to samples from patients, animal models, and cell cultures treated with a drug or a drug candidate. Also disclosed are methods for determining the usefulness of analytes, e.g. cytokines, for acting as diagnostic and monitoring markers for inflammatory bowel disease in the various methods of the invention.
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