ATTENUATED VACCINES TO PROTECT AGAINST TICK-BORNE EHRLICHIA SPECIES INFECTIONS

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United States of America Patent

SERIAL NO

15544090

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Abstract

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Attenuated vaccines to protect vertebrate animals and people against tick-born rickettsial, Ehrlichia and Anaplasma species infections is disclosed. Also disclosed are methods to modify the organism to achieve the desired immunity through the modification of a novel genetic region involved in pathogenesis. These compounds represent a needed vaccine against an organism causing life-threatening febrile illness in humans and animals, and also represent the potential to develop new classes of drugs targeting the gene products of genes Ech_0660, Ech_0379, and Ech_0230, and their homologs of other related rickettsial pathogens.

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Patent Owner(s)

Patent OwnerAddress
KANSAS STATE UNIVERSITY RESEARCH FOUNDATION2005 RESEARCH PARK CIRCLE STE 105 MANHATTAN KS 66502

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHENG, Chuanmin Manhattan, US 3 0
GANTA, Roman R Manhattan, US 6 0
GANTA, Suhasini Manhattan, US 3 0
JAWORSKI, Deborah Stillwater, US 7 1
NAIR, Arathy D S Manhattan, US 3 0

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