Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

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United States of America Patent

PATENT NO 10227343
APP PUB NO 20180022745A1
SERIAL NO

15547775

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Abstract

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Compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.

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Patent Owner(s)

  • VANDERBILT UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bronson, Joanne Princeton, US 2 19
Conn, P Jeffrey Brentwood, US 130 642
Emmitte, Kyle Nashville, US 1 10
Engers, Darren W Nashville, US 53 231
Engers, Julie Nashville, US 2 20
Hopkins, Corey R Nolensville, US 29 287
Lindsley, Craig W Brentwood, US 185 979
Niswender, Colleen M Brentwood, US 26 258
Panarese, Joe Malden, US 3 29
Wu, Yong-Jin Princeton, US 54 297

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