Nanocomposites, methods of making same, and applications of same for multicolor surface enhanced raman spectroscopy (SERS) detections

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United States of America Patent

PATENT NO 10830767
APP PUB NO 20180024126A1
SERIAL NO

15697055

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Abstract

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A method of making at least one nanocomposite for surface enhanced Raman spectroscopy (SERS) detection of a target of interest includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer, wherein the Raman reporter molecule layer comprises Raman reporter molecules that are detectable by the SERS; coating a thiolated polyethylene glycol (PEG) layer on the assembled Raman reporter molecule layer; and conjugating the coated thiolated PEG layer with molecules of an antibody to make the at least one nanocomposite.

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Patent Owner(s)

  • BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS N. A.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biris, Alexandru S Little Rock, US 58 406
Nima, Zeid Little Rock, US 7 10
Xu, Yang Little Rock, US 430 4253

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