NOVEL CHO INTEGRATION SITES AND USES THEREOF

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United States of America Patent

SERIAL NO

15783525

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Abstract

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Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER RD TARRYTOWN NY 10591-6707

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burakov, Darya Yonkers, US 40 163
Chen, Gang Yorktown Heights, US 891 7739
Fandl, James P LaGrangeville, US 79 1642
Shen, Ying Yorktown Heights, US 96 849

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