METHODS FOR PREDICTING THE RESPONSIVENESS OF A PATIENT AFFECTED WITH MALIGNANT HEMATOLOGICAL DISEASE TO CHEMOTHERAPY TREATMENT AND METHODS OF TREATMENT OF SUCH DISEASE

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United States of America Patent

SERIAL NO

15550394

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Abstract

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The present invention relates to antagonists of GDF11, for use in the treatment of malignant hematological disease, such as Acute Myeloid Leukemia (AML). The present invention also relates to a method for predicting the responsiveness of a patient affected with malignant haematological disease, such as Acute Myeloid Leukemia, to a chemotherapy treatment.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS CEDEX 16 75794
UNIVERSITE DE NANTES1 QUAI DE TOURVILLE B P 13522 NANTES CEDEX 1 44035
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE D'ANGERS40 RUE DE RENNES ANGERS 49100
UNIVERSITE PARIS DESCARTES12 RUE DE L'ECOLE DE MEDECINE PARIS 75006
CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS4 RUE LARREY 49933 ANGERS CEDEX 9
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP)3 AVENUE VICTORIA PARIS F-75004
FONDATION IMAGINE24 BOULEVARD DU MONTPARNASSE PARIS 75015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BARDET, Valérie Paris, FR 1 0
CRUZ-MOURA, Ivan Paris, FR 3 2
DUSSIOT, Michaël Paris, FR 1 0
HERMINE, Olivier Paris, FR 33 109
IFRAH, Norbert Cedex 1 Nantes, FR 1 0
TAMBURINI, Jérôme Paris, FR 2 0
TROVATI, MACIEL Thiago Paris, FR 7 87

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