Techniques for controlling distance between a sample and sample probe while such probe liberates analyte from a sample region for analysis with a mass spectrometer

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United States of America Patent

PATENT NO 10134572
APP PUB NO 20180033597A1
SERIAL NO

15225585

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Abstract

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A system includes a mass spectrometer and associated sample interfacing equipment. The sample interfacing equipment includes a platform structured to support a sample thereon, a fluid source, a high voltage source, a dispensing probe electrically coupled to the high voltage source and defining a fluid dispensing passage therethrough, a collection probe defining a collection passage therethrough, a sensing arrangement coupled to the dispensing probe, and control logic responsive to the sensing arrangement to control distance between the dispensing probe and the sample. The dispensing probe facilitates formation of one or more ionized sample analytes when dispensing the fluid through the dispensing passage proximate to the sample on the platform. The collecting probe receives at least some of the one or more ionized sample analytes to pass through the collection passage into the mass spectrometer for analysis.

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Patent Owner(s)

  • BATTELLE MEMORIAL INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Laskin, Julia Richland, US 8 43
Liyu, Andrey V Pasco, US 6 29
Nguyen, Son N Richland, US 3 7

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