MODIFIED CANCER CELL LINES AND USES THEREOF

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United States of America Patent

SERIAL NO

15667067

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Abstract

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The present invention relates to modified cancer cell lines, wherein the ST3Gal1 glycosyltransferase expression is reduced or inhibited. The use of the modified cancer cell lines with suppressed ST3Gal1 glycosyltransferase to screen a potential cancer therapeutic is provided. The suppression of ST3Gal1 glycosyltransferase expression, with or without an anti-cancer agent is also provided to inhibit the growth of cancer cells in a subject.

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Patent Owner(s)

Patent OwnerAddress
CHANG GUNG MEMORIAL HOSPITAL LINKOUNO 5 FUXING ST GUISHAN DIST TAOYUAN CITY 333

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fan, Tan-Chi Taoyuan City, TW 4 9
Hung, Jung-Tung Taoyuan City, TW 3 42
Lin, Wen-Der Taoyuan City, TW 1 0
Yu, Alice L Taoyuan City, TW 20 165

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