Primers, probes and methods for sensitive, specific detection and monitoring of HIV-1 and HCV

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United States of America Patent

PATENT NO 10858711
APP PUB NO 20180037961A1
SERIAL NO

15553083

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Abstract

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Primers and probes for detecting an RNA virus, including HIV, HIV-1 subtypes of the M and O groups, and HCV, in a sample. The primers and probes can be used for monitoring the efficacy of anti-retroviral treatment in a subject infected with HIV and/or HCV, and for detecting acute HIV-1 infection, and/or acute HCV infection, in a subject. Included are inner, middle and outer primers that can be used in PCR, including triple nested PCR in a single tube. The methods are highly sensitive and specific, allowing for detection of as few as 4 copies of virus in a sample.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF WASHINGTON4545 ROOSEVELT WAY NE SUITE 400 SEATTLE WA 98105-4721

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Zhu, Tuofu Seattle, US 1 0

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