Flow cytometry using hydrodynamically planar flow

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United States of America Patent

PATENT NO 10900885
APP PUB NO 20180038783A1
SERIAL NO

15537744

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Abstract

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According to various aspects, a flow system for transporting microparticulate samples in a hydrodynamically planar flow in a selected flow direction includes a flow chamber extending in the flow direction, having first and second apertures on opposed surfaces of the flow chamber. A sheath-fluid channel has first and second branches to carry the sheath fluid into the flow chamber through the first aperture and having orientations separated by less than about 15° at the first aperture; and third and fourth branches to carry the sheath fluid through the second aperture and having orientations separated by less than about 15° at the second aperture. In some examples, guide channels extend from the apertures substantially perpendicular to the flow chamber at the apertures, and sheath-fluid channel supply sheath fluid to the guide channels. Flow systems can be used in image flow cytometers for observing microparticulate samples, e.g., using scanning irradiation.

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Patent Owner(s)

Patent OwnerAddress
MIFTEK CORPORATION1231 CUMBERLAND AVE STE H WEST LAFAYETTE IN 47906

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kayou, Tsukasa Hamamatsu, JP 1 12
Masuda, Yuji Hamamatsu, JP 70 383
Robinson, J Paul West Lafayette, US 26 325
Yamamoto, Masanobu West Lafayette, US 144 2343

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