Pharmaceutical Composition of Killed Cells with Substantially Retained Immunogenicity
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United States of America Patent
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Oct 2, 2017
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Feb 19, 2010
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Abstract
The present invention relates to a lyophilized composition comprising killed cancer cells with substantially retained immunogenicity and morphology, an intracellular cryopreservative such as trehalose and an extracellular cryopreservative such as polyvinylpyrrolidone. The present invention also relates to a process for the preparation of said lyophilized composition. The lyophilized composition of the present invention can be used for cancer immunotherapy.
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