Treatment of cancer using a CD33 chimeric antigen receptor

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United States of America Patent

PATENT NO 10851166
APP PUB NO 20180044423A1
SERIAL NO

15689163

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors encoding the same, and recombinant T cells comprising the CD33 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD33 binding domain.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA3600 CIVIC CENTER BOULEVARD 9TH FLOOR PHILADELPHIA PA 19104
NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ebersbach, Hilmar Erhard Basel, CH 10 384
Huber, Thomas Basel, CH 242 3963
Jascur, Julia Basel, CH 8 219
Richardson, Celeste Cambridge, US 19 350
Singh, Reshma Cambridge, US 20 679
Song, Huijuan Shanghai, CN 13 344
Wu, Qilong Shanghai, CN 38 721
Zhang, Jiquan Shanghai, CN 14 368

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