Bubble-induced color doppler feedback during histotripsy

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United States of America Patent

PATENT NO 11058399
APP PUB NO 20180049719A1
SERIAL NO

15713441

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Abstract

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A Histotripsy therapy system is provided that can include any number of features. In some embodiments, the system includes a high voltage power supply, a pulse generator electrically coupled to at least one signal switching amplifier, at least one matching network electrically coupled to the signal switching amplifier(s), and an ultrasound transducer having at least one transducer element. The Histotripsy therapy system can further include an ultrasound Doppler imaging system. The Doppler imaging system and the Histotripsy therapy system can be synchronized to enable color Doppler acquisition of the fractionation of tissue during Histotripsy therapy. Methods of use are also described.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF MICHIGAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cain, Charles A Ann Arbor, US 34 2542
Maxwell, Adam D Ann Arbor, US 28 77
Miller, Ryan M Ann Arbor, US 11 96
Xu, Zhen Ann Arbor, US 100 1093

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